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          Smoking and hepatitis in patients          

infected with C                           
 
 

 

 

The study says that smoking is a significant cause inflammation of the liver, especially in patients infected with CNN, according to a study published in the journal Gut in 2003.

The study was conducted between February 1998 and September 1999 in France of 224 patients infected with chronic C included questions and a referendum well as taking into

The same liver to assess the impact of smoking on infected with hepatitis C chronic. Referendum included the following questions:

Age at start smoking, how long they smoked, and the number of cigarettes smoked, which used to a day in the six months before the study. Patients also questioned the amount of alcohol Cherbbha normal day and then take samples of the liver of patients.

The study was conducted on 152 men and 92 women an average age under 46 years. No one in the study was also a patient infection hepatitis B virus or loss of immune disease "AIDS".

Liver samples were analyzed and classified according to the degree of liver inflammation and fibrosis. It was found that the proportion of patients with hepatitis violent increased by a disproportionate amount of tobacco used Day found inflammation in the medium-to heavy 62% of patients who smoked cigarettes between one and five tenth day, but almost 82% of patients who smoked more than 15 cigarettes a Today. The Committee found that the proportion of the increased inflammation increased tobacco consumption.

Study has shown that 59% of third-smokers suffer from inflammation of the liver medium-to heavy compared with 67.4% of smokers (1-10 pack of cigarettes per year), 75.5% of moderate smokers (one pack of ten to 20 per year) and 84.6 Acharhon% of smokers (more than 20 pack in the year.)

Because the people who smoked were likely to drink alcohol, and to ensure that their data had been confident and not affected by the consumption of alcohol Ooavaml age (a known risk factors for fear of the liver), was re-analysis of results showed that over the age of 50 and more accustomed to drinking 20 grams of alcohol a day (equivalent to half a pint beer) and smoking more than five ten cigarettes a day leads to inflammation of medium-to heavy liver.

But

Found no association between smoking and cirrhosis of the liver.

(Only life in excess of 50, drinking more than 30 grams of alcohol a day and extended C infection were found to be influential factors).

Researchers also observed that the quick impact of smoking on the liver, perhaps because of the role of the liver to get rid of nicotine.

Despite the fact that smoking was not associated with increased risk of fibrosis, the researchers believe that this can be interpreted that the period of C infection known only half the sample and may not overlap completely duration of smoking.

The study concluded that

Stop or reduce smoking ... recommended in Almrdyalmassapin acute chronic viral hepatitis C. ""

Ibid full:

Hezode C et al Impact of smoking on histological liver lesions in chronic hepatitis C Gut, 52:126-129, 2003.